Top 10 Xeomin Aftercare Tips for Smoother, Youthful Skin

If you’ve chosen Xeomin to smooth fine lines and rejuvenate your appearance, you’re already on the right path toward refreshed, youthful skin. But achieving the best possible outcome doesn’t end with your appointment.

Following the right Xeomin aftercare tips can make a significant difference in the effectiveness, longevity, and safety of your results.

At Express Med Spa, patient education is key to lasting beauty. This guide is designed to help you understand the most important aftercare steps, with clear, expert-backed explanations, so you can feel confident in your skin and protect your investment.

Top 10 Xeomin Aftercare Tips You Should Follow

1. Remain Upright for at Least 4 Hours After Treatment

After receiving Xeomin injections, it’s important to remain upright — no lying down, reclining, or bending forward — for at least four hours. This allows the neurotoxin to properly settle into the targeted muscles without the risk of migration.

If the product moves from the intended injection sites, it could lead to uneven results or complications like eyelid drooping. Staying upright ensures the best chance for Xeomin to work as expected and provide smooth, symmetrical results.

2. Do Not Touch, Rub, or Massage the Treated Areas

It’s natural to want to check or touch your face after a cosmetic procedure, but post-Xeomin, your hands should stay away. The injection sites need time to close and begin healing without interference.

Touching or rubbing the treated area can spread Xeomin into unintended muscles, causing asymmetry or reduced results. It also increases the risk of irritation and infection, especially in the first 24 hours.

3. Hold Off on Exercise for 24 Hours

While regular exercise is great for your health, it’s best to avoid workouts for a full 24 hours after your Xeomin appointment. Physical exertion increases blood flow and body temperature, which can interfere with product placement.

High-intensity activity could also lead to facial redness, swelling, or bruising at the injection sites. Waiting a day helps ensure the neurotoxin stays where it’s needed and your recovery is smooth.

4. Avoid Wearing Makeup for 4 to 6 Hours

After Xeomin injections, your skin will have micro-punctures that are vulnerable to bacteria. Applying makeup too soon can increase the chance of irritation, clogged pores, or infection.

Allow at least 4 to 6 hours before applying any cosmetics, and use clean tools when you do. If possible, skip makeup entirely for the rest of the day to give your skin a chance to breathe and begin the healing process naturally.

5. Avoid Alcohol Consumption for 24 Hours

Alcohol may thin your blood and dilate blood vessels, which increases the risk of bruising and swelling in the hours after Xeomin injections. It also dehydrates your skin, which can hinder recovery.

To support healing and minimize any unwanted side effects, avoid wine, beer, or cocktails for at least a day. Instead, drink plenty of water and eat nourishing foods that support skin health and repair.

6. Apply Cold Compresses Only If Necessary

A cold compress can help reduce mild swelling or bruising, but it must be used carefully. Never apply ice directly to the skin, and avoid putting too much pressure on the injection area.

If you choose to use a cold compress, wrap an ice pack in a soft cloth and apply it for short intervals. This can soothe discomfort without disturbing the product or irritating your skin further.

7. Postpone Skincare Treatments for at Least 7 to 10 Days

Skincare treatments like facials, chemical peels, or microneedling can disrupt the settling process of Xeomin and increase sensitivity. Your skin needs time to heal before undergoing any additional treatments.

Wait at least one week — preferably 10 days — before scheduling anything beyond your basic skincare routine. This ensures that Xeomin takes full effect and minimizes the risk of complications.

8. Don’t Expect Instant Results – Be Patient

Unlike dermal fillers, Xeomin doesn’t show immediate results. You’ll typically begin to see changes in about 3 to 5 days, with full improvement around the 7to 10-day mark.

This delay is normal and expected. During this time, the neurotoxin is gradually relaxing the targeted muscles, leading to a smoother and more refreshed look. Stay consistent with your aftercare and trust the process.

9. Practice Back-Sleeping for the First Few Nights

How you sleep after Xeomin matters more than you might think. Pressing your face into a pillow can cause the product to migrate or settle unevenly.

Try to sleep on your back with your head elevated for the first few nights. This sleeping position helps maintain even product distribution and reduces facial swelling while you rest.

10. Attend Your Follow-Up Appointment

Follow-up visits are a key part of your Xeomin journey, especially if it’s your first time. They allow your provider to evaluate your results, address concerns, and make any necessary adjustments.

At Express Med Spa, we recommend returning around 10 to 14 days post-treatment. This ensures your results are optimized and that you’re happy with your final look.

Possible Xeomin Side Effects

• Redness or slight swelling at injection sites
• Small bumps or tenderness
• Mild bruising
• Temporary headache
• A feeling of tightness or heaviness in the treated areas
• Drooping eyelids (ptosis)
• Uneven smile or brow height
• Muscle weakness beyond the intended area

At Express Med Spa, we prioritize your safety and comfort. Always reach out if you’re unsure about a reaction or need extra guidance.

Bonus Tips to Enhance and Extend Xeomin Results

Maximize your results by complementing your treatment with healthy habits:

• Stay well-hydrated: Water supports skin elasticity and cellular function.
• Eat antioxidant-rich foods: Include berries, green leafy vegetables, and omega-3 fatty acids to fight skin-aging free radicals.
• Stick to a consistent skincare routine: Use gentle cleansers, moisturizers, and SPF daily. Avoid harsh exfoliants or retinoids for at least a few days post-treatment.
• Limit sun exposure: UV damage accelerates aging and may reduce the duration of your Xeomin results. Always wear SPF 30 or higher.

Long-term, these habits will not only enhance your Xeomin outcomes but also support overall skin health.

Your Next Step to Smooth, Youthful Skin

The results you get from Xeomin depend as much on the aftercare as on the injection itself. By following these Xeomin aftercare tips, you’re actively participating in the success of your treatment and helping your skin stay smooth, youthful, and natural-looking for months.

At Express Med Spa Frankfort and other branches, we’re here to guide you every step of the way. From personalized consultations to comprehensive aftercare plans, our experienced team ensures that you feel confident, supported, and glowing — inside and out.

If you’re ready for a smoother, more refreshed look or have questions about your post-treatment care, we’re just a call or click away.