Letybo vs Botox: What’s the Difference and Which Is Right for You?
Choosing between Letybo and Botox isn’t just about picking a name—it’s about understanding how each option aligns with your skin goals, budget, and timeline. These two wrinkle relaxers are making waves in cosmetic dermatology for good reason.
At Express Med Spa, our role is to break down the science, pros, and practical insights so you can move forward with clarity and confidence. Whether you’re new to neuromodulators or a seasoned pro, there’s a new contender in town worth considering.
What is the Difference Between Letybo vs Botox?
While both are botulinum toxin type A formulations, Letybo may be newer to the U.S. market and often more affordable. Botox has long been the go-to for decades and has earned trust for its consistent, time-tested results.
The decision often comes down to onset speed, personal preference, and pricing. Letybo and Botox are botulinum toxin type A injectables, and both work by temporarily relaxing facial muscles to smooth wrinkles and fine lines.
Letybo vs. Botox: Key Differences
Feature | Letybo | Botox |
Manufacturer | Hugel (South Korea) | Allergan (USA) |
FDA Approval Date | 2023 (U.S.) | 2002 (Cosmetic Use) |
Onset Time | ~3 days | ~4-7 days |
Duration | 3-4 months | 3-4 months |
Cost per Unit | Lower | Higher |
Diffusion Rate | May have lower spread | Controlled, consistent spread |
What is Letybo?
Letybo is a botulinum toxin type A product developed to relax dynamic facial muscles that cause fine lines and wrinkles. It has been widely used in Asia and Europe and recently gained FDA approval in the U.S.
It works by temporarily relaxing the nerve signals that prompt muscle contractions—softening the appearance of crow’s feet, areas like the forehead, and frown lines. Letybo works much like Botox and provides a trusted alternative to Botox.
Benefits of Letybo: This New Botox Alternative
- Lower price point for similar effects
- Noticeable results within a few days
- Preferred by many first-time users
- Clean formulation, backed by global clinical use
Letybo injection is excellent for those new to neuromodulators or looking to maintain results more affordably without sacrificing quality.
Clinical studies have shown improvements within a few days, and studies have shown that Letybo delivers results compared to Botox with potential cost savings depending on the number of units injected.
Know more about what is Letybo injection treatments in our guide.
What Is Botox?
Botox is the original household name in injectable treatments. Used since the early 2000s for cosmetic purposes, it offers reliable, smooth results and is frequently used not just for facial aesthetics but also for conditions like TMJ, migraines, and hyperhidrosis.
Benefits of Botox
- Time-tested and FDA-approved since 2002
- Predictable and consistent outcomes
- Trusted by both providers and patients worldwide
- Highly versatile for both medical and aesthetic concerns
Many patients stick with Botox because they know exactly how it will work for them—especially those with long-term treatment histories. Botox’s effects can also extend to various areas of the face and remain the gold standard in cosmetic injectables.
At Express Med Spa, we also use Xeomin, one of the best Botox alternatives for clients who prefer a cleaner formulation with fewer additives, offering similar results for softening fine lines and wrinkles.
Why Consider Letybo?
Introducing Letybo as a more budget-friendly option with results that take effect quickly. It’s a great fit for younger patients, beauty newbies, or anyone looking to maintain their glow without stretching their wallet.
Whether you’re looking to soften fine lines, reduce wrinkles, or explore cosmetic injectables for the first time, Letybo offers a promising choice. At Express Med Spa, we’ve seen a rising interest among those seeking professional outcomes with flexible pricing.
How Does Letybo Stack Up Against Botox?
The effects of Botox and Letybo are similar. The primary differences stem from brand legacy and pricing. If you’re looking for fast results at a friendlier cost, Letybo is a great option.
If you value decades of documented reliability, Botox may give you extra peace of mind. All offer excellent wrinkle reduction when administered by skilled injectors.
Try alternating between the two if you’re open to exploring what works best for your skin. Just ensure consistency in your injector—that expertise matters more than the brand. Like Botox, Letybo depends on the correct dosing and placement to ensure optimal results.
Are Letybo and Botox Safe?
Yes, both treatments are very safe when performed by trained professionals. At Express Med Spa, every injection is done by licensed clinicians who understand facial anatomy, dilution protocols, and patient goals. You can expect minor side effects like mild redness or tenderness at the injection site, which typically resolve within a day or two.
FAQs
How long does Letybo last?
Around 3 to 4 months. This aligns with what most patients experience with Botox.
Is Letybo better than Botox?
It depends on your goals. Letybo often wins on affordability and quick onset, while Botox delivers predictable, established results.
Can I switch from Botox to Letybo?
Absolutely. Many patients switch between the two without issue. Let your injector guide you based on how your body responds. Adding Letybo to your routine can offer new options for patients exploring cost savings without compromising on quality.
Is Letybo as good as Botox?
In clinical performance, yes. Both are botulinum toxin type A products. The results depend more on dosage, technique, and injector experience.
Why is Letybo so cheap?
Letybo is newer to the U.S. and priced competitively. It also doesn’t have the decades of brand recognition that Botox enjoys yet. The cost of Botox may be higher per unit, but unit efficiency and results may vary by individual.
How much is Letybo vs Botox?
Prices vary, but Letybo typically runs 15-25% less per unit at Express Med Spa, making it a cost-effective alternative.
Which One is Right for You?
If cost and fast results are your top priorities, Letybo could be your go-to. If you want something proven and precise, Botox remains the trusted choice. Either way, you’re in expert hands at Express Med Spa.
We’ll tailor your treatment to your facial structure, lifestyle, and aesthetic goals. Whether Letybo or Botox, we offer Letybo and Botox at all locations and recommend based on your unique skincare needs.
Letybo and Botox both offer smooth, rejuvenated skin without surgery, downtime, or guesswork. Choosing the right one depends on your priorities.
At Express Med Spa Shorewood, we’re here to educate, not upsell. Book a consultation and let our experienced injectors help you glow with confidence whether it’s your first visit or your fifteenth.
Not ready to commit? That’s exactly why we offer free consults.
🧬 No pressure. Just personalized care that fits your goals.


You don’t have to guess what treatment is right for you. Book a complimentary consultation and let our licensed professionals help you choose the safest and most effective option. We will walk you through your options and help you decide what makes the most sense for your skin, goals, and budget.Express Med Spa Team
Not ready to commit? That’s exactly why we offer free consults.
🧬 No pressure. Just personalized care that fits your goals.