Client receiving a Letybo injection at Express Med Spa, a cost-effective Botox alternative for wrinkle reduction.

When it comes to wrinkle injections, most people immediately think of Botox. But a new name is gaining attention in 2025: Letybo treatment. This FDA-approved botulinum toxin type A injectable has been trusted overseas for years as part of K beauty treatments, and it is now available across the U.S.

Naturally, the first question people ask is: What is the Letybo price, and is it actually cheaper than Botox’s?

How Much Does Letybo Cost?

Close-up of a Letybo botulinum toxin injection vial held by a licensed professional at Express Med Spa
Letybo botulinum toxin vial prepared for professional wrinkle-reduction treatment at Express Med Spa.

In 2025, the average Letybo price per unit in the U.S. is $9 to $13. Most people need around 20 units to treat glabellar lines which are the frown lines between the eyebrows. That puts the typical treatment cost around $180 to $260 per session.

For comparison:

  • Botox price per unit: $12 to $16, though some areas of the country average $12 per unit or even $18 per unit
  • Average Botox session for frown lines: $240 to $320

That means Letybo injections offers a lower price point, generally 10 to 20 percent cheaper than Botox per treatment, which adds up quickly if you are maintaining your results three to four times a year.

Pricing varies depending on the number of units needed and the strength of your targeted facial muscles. Men typically need higher doses than women. Always look at the total treatment cost rather than just cost per unit.

What Is Letybo?

Letybo (letibotulinumtoxinA wlbg) is a purified botulinum toxin type A, the same family as Botox, Dysport, and Xeomin. It is manufactured by Hugel, a global aesthetics company, and was approved by the FDA in 2024. 

Like Botox, it is used to treat moderate to severe glabellar lines by temporarily blocking nerve signals to the muscles that cause wrinkles.

What sets it apart:

  • High purity 95 percent with fewer accessory proteins which may reduce the risk of resistance
  • Highly purified formula that many patients who have previously used other toxins now prefer
  • Fast amount of time to onset with some patients seeing results within a few days and most noticing changes by Day 3
  • Natural-looking results designed for softer effects that do not freeze expression
  • Globally trusted with 31 million vials used in Asia and Europe before it hit the market in the U.S.

For patients at Express Med Spa, Letybo may feel like a refresh button with subtle softening that looks like you, just more rested.

Letybo Price vs Botox and Other Alternatives

Let’s compare cost, units, and benefits of different wrinkle relaxers compared to other neuromodulators:

ProductAvg Price per UnitUnits for Frown LinesTotal CostLongevityKey Advantage
Letybo$9 to $1320$180 to $26012 to 16 weeksFast onset with a natural finish
Botox$12 to $1620$240 to $32012 to 16 weeksMost recognized name
Dysport$4 to $6 (needs 2.5x units)50$200 to $30012 to 16 weeksSpreads quickly and works well for broad areas
Xeomin$10 to $1420$200 to $28012 to 16 weeks“Naked” formula with no additives
Botulaxvariesvariessimilarup to 16 weeksPopular in Asia and similar to other neuromodulators

Key Takeaways:

  • Letybo price is almost always lower than Botox and Dysport, but clinical trials show results are comparable
  • Letybo offers a softer finish like Botox, but at a lower price point
  • Xeomin appeals to patients who prefer fewer additives
  • There are more than 70 neurotoxin competitors globally, but Letybo is now standing out in the U.S.

Want to dive deeper into the differences between these injectables? Check out our full guide on Letybo vs Botox to see which option may be right for you.

Is Letybo Worth the Price?

Yes especially for candidates for Letybo who want a modern and cost effective alternative to Botox without sacrificing results.

Here’s why:

  1. Proven effectiveness
    • Clinical studies show effects of Letybo perform just as well as results of Botox in smoothing deep lines. Some trials even showed slightly higher patient satisfaction scores at four to eight weeks.
  2. Lower upfront cost
    • Saving $40 to $60 per session may not sound huge, but if you keep up with treatments three to four times per year, that is $150 to $200 saved annually.
  3. Natural-looking results
    • Patients often say Letybo feels lighter than Botox, leaving more natural movement.
  4. Safe and effective
    • With millions of treatments worldwide, Letybo is not a risky newcomer. It is a safe and efficacious neuromodulator with strong data supporting its use.

4 Simple Ways to Maximize Your Results

A great journey with Letybo is not just about the product but also about how you maintain your results. Here’s what experienced injectors recommend:

Stick to the right schedule

Results last 12 to 16 weeks, and for some, full results typically last six months based on individual factors like metabolism. Do not wait until all movement comes back. Keeping up with treatments helps maintain smoother results.

Take skincare seriously

Neuromodulators relax wrinkles but do not improve skin texture. Pairing your treatment with medical grade skincare enhances the overall effect.

Avoid bargain shopping

Yes, Letybo offers value, but do not chase the cheapest injector. Always look for a board-certified injector or board-certified plastic surgeon who reviews your medical history and understands your goals.

Protect your results after treatment

  • Avoid rubbing the area to prevent spread to muscles that cause other movements
  • Skip workouts for a day to ensure optimal effects of Letybo
  • Allow time for your body to settle before judging results. Remember, full results appear in 1 to 2 weeks

Combine with other non invasive treatments

Pairing Letybo with dermal fillers, facials, or energy devices enhances the benefits of Letybo and helps achieve a refreshed appearance.

FAQs About Letybo Price and Treatments

How many units of Letybo will I need?

  • Glabellar lines: 20 units which is the standard FDA approval protocol
  • Forehead lines: 10 to 20 units
  • Crow’s feet: 12 to 24 units
    Treatment plans vary based on individual anatomy.

Does insurance ever cover Letybo?

No. Cosmetic neuromodulators are not covered, even if they are safe and efficacious.

Is Letybo cheaper if I treat multiple areas at once?

Often yes. Many clinics, including Express Med Spa, offer Letybo packages with bundled pricing.

How long do results last compared to Botox?

Both last 12 to 16 weeks. Some notice onset within a few days with Letybo, compared to how Botox typically takes 3 to 5 days.

Is Letybo a Good Alternative to Botox?

For anyone considering wrinkle relaxers in 2025, Letybo offers the same proven outcomes as Botox at a lower price point. It is safe and effective, backed by millions of treatments, and delivers natural-looking results.

Think of it as a nonsurgical alternative to a mini facelift. It helps smooth moderate to severe glabellar lines, improves confidence, and refreshes your appearance.

At Express Med Spa, patients appreciate being able to choose Letybo as part of their journey with Letybo under the care of a board-certified plastic surgeon or licensed injector.

Book Your Letybo Consultation at Express Med Spa

Ready to see if you are a candidate for Letybo? Schedule a consultation at Express Med Spa in Frankfort, Shorewood, Mount Greenwood, or La Grange. Our providers use safe and efficacious injectable neuromodulators and create personalized plans that fit your goals and lifestyle.

Book an appointment for Letybo today and experience why this purified botulinum toxin is one of the most exciting treatments of 2025.


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Stefanie Drozd, APRN
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