Professional B12 injection for energy and metabolism at Express Med Spa in Chicago

Wellness Injections

B12 Injections

B12 injections boost energy and metabolism. Each B12 shot delivers a concentrated dose of vitamin B12 to help your body convert food into energy, support red blood cell production, and ease fatigue. At Express Med Spa, B12 injections are administered by licensed nurse practitioners across our Chicagoland locations in a quick, in-office visit. Here you will find how B12 shots work, what they cost, and where to book near you.
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Treatment TIme
10-15 min

DownTime

none

RESULTS TIMELINE

Many people feel an energy lift within 24 to 72 hours of a B12 shot.

Result Last

Effects typically last 1 to 4 weeks. A monthly or biweekly shot helps keep your B12 levels steady.

BEST FOR

Fatigue, low energy, metabolism support, B12 deficiency, vegetarian and vegan diets
  • Stefanie Drozd, Full Practice Authority Nurse Practitioner specializing in aesthetic and wellness treatments

    How does a B12 injection work?

    The shot delivers a concentrated dose of vitamin B12 directly into the muscle, bypassing digestion so your body can absorb it fully. B12 helps convert food into energy and supports red blood cell production.

  • Stefanie Drozd, Full Practice Authority Nurse Practitioner specializing in aesthetic and wellness treatments

    What do B12 shots support?

    Patients use B12 injections for steady energy, metabolism support, and mental clarity, and to keep levels up on vegetarian or vegan diets. Many pair them with lipotropic skinny shots during a weight-loss plan.

  • Stefanie Drozd, Full Practice Authority Nurse Practitioner specializing in aesthetic and wellness treatments

    What happens at the visit?

    A nurse practitioner gives the intramuscular shot, usually in the upper arm, in a quick 10 to 15 minute visit. There is no downtime, so you can head straight back to your day.

  • Stefanie Drozd, Full Practice Authority Nurse Practitioner specializing in aesthetic and wellness treatments

    When will I feel it, and how long does it last?

    Many people feel an energy lift within 24 to 72 hours. Effects typically last 1 to 4 weeks, so a biweekly or monthly shot keeps your levels steady.

  • Stefanie Drozd, Full Practice Authority Nurse Practitioner specializing in aesthetic and wellness treatments

    B12 shot or oral supplement?

    Oral B12 has to survive digestion, where absorption can be limited. An injection delivers the full dose directly, which is why patients who feel little from tablets often notice a real difference from the shot.

    About This Treatment


    Here is a closer look at how a B12 shot works in the body, what it supports, what the quick injection visit is like, and how it compares to taking an oral B12 supplement, so you know exactly what to expect before you book.

    Treatment Pricing

    From
    Price
    $39

    Vitamin B12 Injection from $39 per shot. Packages and membership pricing may lower the per-shot cost for regular visits. Ask your nurse practitioner about a schedule that fits your energy goals. Pricing is subject to change.

    View our full med spa price menu

    *Pricing is subject to change.


    Who B12 Injections is For

    Good Candidates? Is This Right for You?

    B12 injections, also called B12 shots, are popular with patients who feel tired, foggy, or run-down and want an energy and metabolism boost. A nurse practitioner gives the intramuscular shot in a quick visit.


    Chicagoland Med Spa Reviews

    What Clients Say About B12 Injections

    • This place is legit the best. Even after moving from Chicago, I fly in from Vegas to get services and it is totally worth it. Vegas has some of the top med services and surgeons in the country, but pales in comparison to Stef & her staff. My daughter and her friends also drive from Indiana & Michigan on the regular. My niece originally told my daughter, who then told me about them and I couldn’t be happier. From B-12 shots to Botox to thread lifts, they are always on the cutting edge of new products & procedures. And my daughter swears she is the only one she will let fill her lips, so natural you can’t even tell. Cannot recommend enough.
      Donna Kenny
      Google Review
    • What a great treasure I stumbled upon while in Frankfort today! I had been looking for a med spa for awhile now where I could get vitamin B12 and vitamin D shots, and I found this place while shopping around! They were able to take me in right away and Stephanie was just wonderful! And their Botox prices! Woo woo! Very clean, friendly staff, and great atmosphere! I found my new spot so I don’t have to drive downtown anymore!
      Susan Lyons
      Google Review
    • Debated wether to get under eye filler. Made an appt for a free consultation. My only suggestion was..I dont want to look fake. Stefanie, the owner, was absolutely wonderful!! She took her time explaining the procedure and never felt rushed at all. My eye filler looks and feels natural. Ive beem back for Vit b12 injections as well!!
      Kathleen Cavallone
      Google Review
    • Sarah Walker | Rating: 5 /5
      “Girls are extremely nice and shot was painless!! Definitely will be coming back!”
      Date: 2024-08-12 21:17:03
      Sarah Walker
      Google Review
    • Maddy Barnes
      I went to the Mt. Greenwood location and I couldn’t be more happier! I walked in super nervous since it was my first time and walked out feeling so pleased with the service. Hayley was the nurse who did my injections and she was so amazing! She made me less nervous and talked me through every step she was doing! So grateful for my first time experience and would DEFINITELY go back again!
      Maddy Barnes
      Google Review
    • I wish google allowed video reviews because I can't even begin to put into words how amazing my experience has been with Express Med Spa. I had connected with Express Med Spa through their “Be Well Package” in hopes of losing weight due to a recent dive in my annual blood work with my GP. Not only have I lost 25lbs since September (without a prescription) but the B12 and Vitamin D injections have allowed me to be migraine free for months (something that has not happened in over 20 years). I feel great and have seen a significant shift in my mood. I highly recommend Express Med Spa!!! **My daughter also had her ears pierced at Express Med Spa – they did a great job calming her nerves and she left so happy!!!
      Sarah Shaughnessy
      Google Review

      Contraindications & Risks / Side Effects

      Contraindications
      Known allergy to cobalt or cobalamin (vitamin B12).
      Leber hereditary optic neuropathy.
      Pregnancy or breastfeeding without provider guidance.
      Active infection or feeling unwell on the day of your visit.

      Risks / Side Effects

      Temporary soreness, redness, or a small bruise at the injection site.
      Mild itching or, rarely, an allergic reaction.
      Occasional mild, short-lived digestive upset.

      Chicagoland Medical Spa

      EXPRESS MED SPA LOCATIONS

      Experience our expert aesthetic treatments and personalized care at our convenient Express Med Spa locations. Whether you're looking for Botox, weight loss programs, or laser hair removal, we provide advanced beauty and wellness services across our four premier locations.
      Express Med Spa Shorewood IL medical spa exterior serving patients from Joliet, Plainfield, and Will County.

      Express Med Spa Frankfort, IL

      Our
      clinic serves Will County with nurse practitioner-led Botox,
      fillers, GLP-1 weight loss,
      and laser hair removal.

      11 S White St #104
      Frankfort, IL
      60423
      (877) 363-3772


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      Express Med Spa Shorewood IL medical spa exterior serving patients from Joliet, Plainfield, and Will County.

      Express Med Spa Shorewood, IL

      Our
      clinic serves Joliet, Plainfield, and the I-80 corridor
      with injectables, GLP-1 weight loss,
      and skin care.

      707 W Jefferson St Ste M
      Shorewood, IL
      60404
      (877) 363-3772


      View Express Med Spa Shorewood →

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      Exterior view of Express MedSpa La Grange clinic building showcasing modern medical spa facility.

      Express Med Spa La Grange, IL

      Our
      clinic serves the western suburbs with Botox, fillers,
      IV therapy,
      and GLP-1 medical weight loss.

      320 W Burlington Ave
      La Grange, IL
      60525
      (708) 847-0872


      View Express Med Spa La Grange →

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      Exterior view of Express MedSpa clinic in Mount Greenwood Chicago showing the medical spa building.

      Express Med Spa Mount Greenwood, Chicago IL

      Our Express Med Spa Mount Greenwood
      clinic serves Chicago's South Side and southwest Cook County
      with nurse practitioner-led injectables, GLP-1 weight loss,
      and advanced aesthetics.

      3314 W 111th St
      Chicago, IL 
      60655
      (877) 363-3772


      View Express Med Spa Mount Greenwood →

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      VIEW ALL LOCATIONS & COMPARE SERVICES
      Each medical spa location is led by a licensed Nurse Practitioner, with a focus on safe, results-driven care.

      What To Expect

      Pre & Post Treatment Care

      Pre-Care Instructions
      No special prep is needed; you can come in on a normal schedule.
      Tell your provider about your medications, allergies, and health history.
      Mention any past reactions to injections or vitamins.

      Post-Care Instructions

      Resume normal activity right away.
      Apply gentle pressure if the site feels tender.
      Let your provider know about any rash, swelling, or lasting reaction.

      • How B12 Injections Work

        Vitamin B12 is essential to two of the body’s core energy systems: it helps convert the food you eat into usable energy and supports the production of healthy red blood cells that carry oxygen throughout the body. When B12 runs low, the first signs are usually fatigue, brain fog, and a run-down feeling that sleep does not fix.

        A B12 injection delivers a concentrated dose of the vitamin directly into the muscle. Because it bypasses the digestive tract entirely, the full dose is available to your body rather than the fraction that survives absorption from food or tablets. That direct delivery is what makes the shot such a reliable way to restore and maintain healthy B12 levels.

      • What B12 Shots Support

        Most patients book B12 injections for energy and metabolism support: steadier energy through the week, sharper focus, and help converting nutrients efficiently during a weight-loss effort. B12 also supports nerve function and red blood cell health, which is why levels matter well beyond how energetic you feel.

        B12 shots pair naturally with other wellness injections at Express Med Spa. Patients on a weight-loss plan often combine them with lipotropic skinny shots for fat-metabolism support, and patients focused on deeper cellular energy and recovery sometimes alternate B12 with NAD+ injections.

      • What to Expect at Your B12 Visit

        A B12 appointment at Express Med Spa is one of the quickest visits on the menu. After a brief check-in with a nurse practitioner to confirm the shot fits your goals and health history, the injection itself takes only a moment, usually in the upper arm or hip.

        Most visits are done in 10 to 15 minutes, and there is no downtime of any kind. Many patients schedule their B12 shot on a lunch break or on the way to the gym, and regulars are often in and out even faster.

      • When You Will Feel It and How Long It Lasts

        Many people notice an energy lift within 24 to 72 hours of a B12 shot, though the timing varies with how low your levels were to begin with. Patients starting from a genuine deficiency often describe the change as the most noticeable.

        The effects of a single injection typically last 1 to 4 weeks. To keep levels steady, most patients settle into a biweekly or monthly cadence, and your nurse practitioner can help you find the schedule that matches your energy goals. Package and membership pricing can lower the per-shot cost for regular visits.

      • B12 Injections vs. Oral Supplements

        Oral B12 works for some people, but it has a built-in limitation: the vitamin must survive the digestive tract, where absorption depends on stomach acid and a protein called intrinsic factor. For many people, especially those with digestive conditions, those taking common acid-reducing or diabetes medications, and adults whose absorption declines with age, only a small fraction of an oral dose is actually absorbed.

        An injection sidesteps all of that by delivering the full dose directly into the muscle. That is why patients who feel little from tablets often notice a clear difference from the shot. If you follow a vegetarian or vegan diet, which limits natural B12 intake, injections are also an efficient way to keep levels where they should be.

        Facial treatment for hydration, glow, and smoother skin texture during a spring appointment at Express Med Spa.

        CommON QUESTIONS

        B12 Injections FAQs