Nurse practitioner preparing a NAD+ injection for cellular energy at Express Med Spa in Chicago

Wellness Injections

NAD+ Injections

NAD+ injections replenish cellular energy. Each shot delivers nicotinamide adenine dinucleotide (NAD+) directly into the body to support mental clarity, metabolism, and healthy aging at the cellular level. At Express Med Spa, NAD+ injections are administered by licensed nurse practitioners across our Chicagoland locations as a quick, in-office alternative to a longer NAD+ IV drip. Here you will find how NAD+ injections work, what they cost, and where to book near you.
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Treatment TIme
15-30 min

DownTime

none

RESULTS TIMELINE

Many patients notice steadier energy and clearer focus within a few days. Benefits build with a regular schedule.

Result Last

Effects are cumulative. A shot every 1 to 2 weeks is common during an initial series, then spaced out for maintenance.

BEST FOR

Low energy, brain fog, metabolism support, healthy aging, post-illness recovery
  • Stefanie Drozd, Full Practice Authority Nurse Practitioner specializing in aesthetic and wellness treatments

    How do NAD+ injections work?

    NAD+ is a coenzyme your cells use to turn food into energy and to run everyday repair. An intramuscular shot delivers it straight into the body, so it does not have to survive digestion first.

  • Stefanie Drozd, Full Practice Authority Nurse Practitioner specializing in aesthetic and wellness treatments

    What do NAD+ injections support?

    Patients use them to support steady energy, mental clarity and focus, metabolism, and healthy aging at the cellular level. It is a whole-body wellness boost rather than treatment for one spot.

  • Stefanie Drozd, Full Practice Authority Nurse Practitioner specializing in aesthetic and wellness treatments

    What happens at the appointment?

    A nurse practitioner reviews your history and goals, then gives the shot in minutes. The visit runs about 15 to 30 minutes with no downtime, so you can head straight back to your day.

  • Stefanie Drozd, Full Practice Authority Nurse Practitioner specializing in aesthetic and wellness treatments

    When will I feel the results?

    Many patients notice steadier energy and clearer focus within a few days. Benefits build with a regular schedule, often a shot every 1 to 2 weeks at first, then spaced out for maintenance.

  • Stefanie Drozd, Full Practice Authority Nurse Practitioner specializing in aesthetic and wellness treatments

    Injection or NAD+ IV drip?

    The shot is quick and fits a short visit; a NAD+ IV drip delivers a larger dose slowly over a longer session. Your nurse practitioner helps you pick based on your goals and time.

    About This Treatment


    New to NAD+ injections? This section walks through how the shot works in the body, what to expect at your visit, when you will notice a difference, and how it compares to a NAD+ IV drip, so you can decide whether the injection fits your energy and wellness goals.

    Treatment Pricing

    From
    Price
    $75

    NAD+ Injection from $75 per shot. Many patients choose a series for cumulative benefit, or step up to a NAD+ IV drip for a larger dose. Ask your nurse practitioner which option fits your goals. Pricing is subject to change.

    View our full med spa price menu

    *Pricing is subject to change.


    Who NAD+ Injections is For

    Good Candidates? Is This Right for You?

    NAD+ injections are a good fit for adults who want a quick, in-office energy and cellular-health boost without the time of an IV drip. A nurse practitioner reviews your history and goals, then gives the injection in minutes.


    Chicagoland Med Spa Reviews

    What Clients Say About NAD+ Injections

    • Erica Lagunas
      I had a fantastic experience at Express Med Spa for my IV therapy! Hayley was professional, friendly, and made me feel completely at ease. I went in for a hydration and vitamin boost, and I genuinely felt a difference afterward—more energized and refreshed. I’ll definitely be coming back and would highly recommend it to anyone looking to feel their best specially with flu season around the corner.
      Erica Lagunas
      Google Review
    • Lana Y. Logan | Rating: 5 /5
      “I am going to start by saying that I had no idea what to expect from my appointment, I was only hoping to get a consultstion for my chronic fatigue, hot flashes and weight gain due to menapause. I also booked an appointment for the hydration IV. Having dealt with breadt cancer 9 years ago and currently dealing with the symptoms related to Crohn's and Lupus, my health is now complicated by menapause. My physician prescribed me estrogen cream (yes, with the knowledge that it's not favorable for someone who had breast cancer) and said that I "just have to get used to the symptoms." So, when Steph and I started talking, there was no doubt in my mind that I found someone who actually heard my frustration. Everything, from Steph's vibe (yes, it's all about the vibes for me), to getting poked for bloodwork and for a hydration fluids (5 out of 5 stars on her skills), to her past experience in oncology (only extra special people can do that job), to her confidence as a nurse, 5 +++ stars all around. As a therapist myself, I can give Steph 100% confidence in client care and thinking outside of the box. I look forward to working with her on an ongoing basis.”
      Date: 2023-08-17 03:25:01
      Lana Y. Logan
      Google Review
    • What a great treasure I stumbled upon while in Frankfort today! I had been looking for a med spa for awhile now where I could get vitamin B12 and vitamin D shots, and I found this place while shopping around! They were able to take me in right away and Stephanie was just wonderful! And their Botox prices! Woo woo! Very clean, friendly staff, and great atmosphere! I found my new spot so I don’t have to drive downtown anymore!
      Susan Lyons
      Google Review
    • Love coming here! B12 shots and lips done by the best!
      Michele Ryan
      Google Review
    • Josie H | Rating: 5 /5
      “So my husband Anthony went in for some emergency IV fluids as well as some couple other things to help him regain some energy he's dealing with some kidney issues and some other things. So when he went in the nurse that took care of him. Steph g was kind courteous and made sure that his needs were met. He said if you could give a 10-star rating he would great place to go great service highly recommend.”
      Date: 2025-07-14 00:39:06
      Josie H
      Google Review
    • Megan Harre
      Seriously… the best place on earth! Erica E and Erica L have transformed me from a tired, worn down, old lady to a confident mom who isn’t afraid of the mirror (or scale!) anymore! Every question, visit and service has been beyond exceptional! Super knowledgeable, kind and comforting! Don’t waste your time going anywhere else!
      Megan Harre
      Google Review

      Contraindications & Risks / Side Effects

      Contraindications
      Pregnancy or breastfeeding.
      Known sensitivity to NAD+ or any injection ingredient.
      Active infection or feeling acutely unwell on the day of your visit.
      Significant heart, liver, or kidney conditions without provider clearance.

      Risks / Side Effects

      Temporary soreness, redness, or a small bruise at the injection site.
      Flushing, warmth, or mild nausea if the dose is given quickly.
      Brief lightheadedness, which usually settles within a few minutes.

      Chicagoland Medical Spa

      EXPRESS MED SPA LOCATIONS

      Experience our expert aesthetic treatments and personalized care at our convenient Express Med Spa locations. Whether you're looking for Botox, weight loss programs, or laser hair removal, we provide advanced beauty and wellness services across our four premier locations.
      Express Med Spa Shorewood IL medical spa exterior serving patients from Joliet, Plainfield, and Will County.

      Express Med Spa Frankfort, IL

      Our
      clinic serves Will County with nurse practitioner-led Botox,
      fillers, GLP-1 weight loss,
      and laser hair removal.

      11 S White St #104
      Frankfort, IL
      60423
      (877) 363-3772


      View Express Med Spa Frankfort →

      Get Directions
      Express Med Spa Shorewood IL medical spa exterior serving patients from Joliet, Plainfield, and Will County.

      Express Med Spa Shorewood, IL

      Our
      clinic serves Joliet, Plainfield, and the I-80 corridor
      with injectables, GLP-1 weight loss,
      and skin care.

      707 W Jefferson St Ste M
      Shorewood, IL
      60404
      (877) 363-3772


      View Express Med Spa Shorewood →

      Get Directions
      Exterior view of Express MedSpa La Grange clinic building showcasing modern medical spa facility.

      Express Med Spa La Grange, IL

      Our
      clinic serves the western suburbs with Botox, fillers,
      IV therapy,
      and GLP-1 medical weight loss.

      320 W Burlington Ave
      La Grange, IL
      60525
      (708) 847-0872


      View Express Med Spa La Grange →

      Get Directions
      Exterior view of Express MedSpa clinic in Mount Greenwood Chicago showing the medical spa building.

      Express Med Spa Mount Greenwood, Chicago IL

      Our Express Med Spa Mount Greenwood
      clinic serves Chicago's South Side and southwest Cook County
      with nurse practitioner-led injectables, GLP-1 weight loss,
      and advanced aesthetics.

      3314 W 111th St
      Chicago, IL 
      60655
      (877) 363-3772


      View Express Med Spa Mount Greenwood →

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      VIEW ALL LOCATIONS & COMPARE SERVICES
      Each medical spa location is led by a licensed Nurse Practitioner, with a focus on safe, results-driven care.

      What To Expect

      Pre & Post Treatment Care

      Pre-Care Instructions
      Eat a normal meal and drink water before your appointment.
      Tell your provider about your medications, allergies, and health history.
      Plan a few extra minutes so the injection can be given slowly and comfortably.

      Post-Care Instructions

      Keep hydrated for the rest of the day.
      Resume normal activity right away.
      Apply gentle pressure if the site feels tender, and let your provider know about any lasting reaction.

      • How NAD+ Injections Work

        NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell in your body. Your cells rely on it for two essential jobs: converting the food you eat into usable energy and powering the enzymes that carry out everyday cellular repair and maintenance. Natural NAD+ levels tend to decline with age, stress, illness, and demanding schedules.

        A NAD+ injection is an intramuscular shot that delivers this coenzyme directly into the body, where it is absorbed without having to pass through the digestive system first. At Express Med Spa, the injection is given by a licensed nurse practitioner as a quick, in-office way to top up NAD+ and support how efficiently your cells produce energy.

      • What NAD+ Injections Support

        Because NAD+ sits at the center of cellular energy production, patients use these injections to support several everyday functions at once:

        • Energy and stamina – supporting steadier day-to-day energy rather than a caffeine-style spike.
        • Mental clarity and focus – many patients describe less brain fog and sharper concentration.
        • Metabolism – supporting the cellular machinery that turns food into fuel.
        • Healthy aging – NAD+ powers the repair enzymes involved in maintaining healthy cells over time.
        • Recovery – a common choice when you are rebuilding energy after illness or a demanding stretch.

        NAD+ injections are a whole-body wellness support, not a treatment aimed at a single area of the face or body.

      • What to Expect at Your Visit

        A NAD+ injection appointment is short and straightforward. Your nurse practitioner first reviews your health history and what you are hoping to get out of the treatment, then administers the injection in just a few minutes. The whole visit typically runs about 15 to 30 minutes.

        There is no downtime. Side effects are usually mild, such as brief soreness at the injection site or a short flushing sensation if the dose is given quickly, and you can return to your normal day right away.

      • When You Will Notice Results

        Many patients notice steadier energy and clearer focus within a few days of their first injection. NAD+ works at the cellular level, so the benefits are cumulative and tend to build with a regular schedule rather than arriving all at once.

        A common approach is a shot every 1 to 2 weeks during an initial series, then spacing treatments further apart for maintenance once you feel the effect. Your nurse practitioner will tailor the cadence to how you respond.

      • NAD+ Injection vs. NAD+ IV Therapy

        Express Med Spa offers NAD+ in two forms. A NAD+ injection is a quick intramuscular shot you can fit into a short visit, which makes it an easy way to stay consistent. NAD+ IV therapy delivers a larger dose slowly through an IV drip over a longer session, which some patients prefer when they want a bigger single dose.

        Neither is automatically better; the right choice depends on your goals, your schedule, and how much time you want to spend in the chair. Many patients also pair NAD+ with B12 injections or IV hydration therapy for broader wellness support. Your nurse practitioner can help you decide which option, or combination, fits best.

        Facial treatment for hydration, glow, and smoother skin texture during a spring appointment at Express Med Spa.

        CommON QUESTIONS

        NAD+ Injections FAQs